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Why CellReg?
As we age, the number of stem cells in most tissues decreases. This leads to degeneration because tissue can no longer be recreated to a sufficient extent. Cell therapy is one of the few ways to stop this and 'naturally' regenerate defective tissue.
The principle is simple: Stem cell-rich tissues serve as donors for stem cell-poor tissues. For example, fat or bone marrow becomes a donor for joints or tendons.
Cell therapy has been used worldwide for around 20 years. The application of highly concentrated cells and their ingredients can cause regeneration of the treated tissue and normalization of the disturbed metabolism. Three effects are believed to be responsible for this:
Homing Effect
Immediately after application, the living stem cells attach to the defective areas that need to be regenerated and transform into local tissue such as cartilage.
Paracrine effect
The applied cells secrete so-called extracellular vesicles, which contain growth factors and thus keep the regeneration effect going
Immunomodulatory effect
Control molecules such as Hif and IGF-1 are cytokines that stimulate cartilage formation and inhibit cell death. Thus, dying cells are revitalized, premature death is prevented and metabolism is normalized.
Cell therapies at a glance
Stem cell therapy with SVF
'Stroma Vascular Fraction'
SVF stands for 'Stroma Vascular Fraction'. This means that a certain proportion of cells from your own fatty tissue is used for the therapy. SVF is obtained through minimally invasive liposuction and then processed in various steps, which concentrates the active ingredients, especially mesenchymal stem cells. The SVF is then injected directly into the affected area.
Cell therapy with PRP
'Platelet Rich Plasma'
PRP stands for 'Platelet Rich Plasma'. This means that your own plasma with platelets is used as active cells. PRP is obtained by simply drawing blood from the arm. The blood is then processed in a centrifuge, which concentrates the active ingredients such as growth factors and other signaling proteins. The PRP is then injected directly into the affected area.
Cell therapy with ACT
'Autologous Cartilage Transplantation'
ACT stands for 'Autologous Cartilage Transplantation'. This means that small samples of the body's own cartilage are propagated in the cell laboratory over several weeks and then replanted in a second minimally invasive operation. Here, mature living cartilage cells called chrondrocytes are applied to defective joint areas.
Cell therapies in comparison
What When How - and what is best for me? This overview is intended to help you with the classification. Ultimately, a medical consultation is essential, as this is the only way to adequately understand the individual initial situation. Cell therapy is a personally adapted treatment!
Main effective portion
Field of use
Frequency of application
Repeatable
New tissue formation
Contains living cells
Side effects
Anesthesia
Restrictions after the procedure
SVF
Stem cells & stromal cells
All tissues (joints, tendons, ligaments, cartilage)
Once
Yes (usually 2-5 years)
Yes (possible)
Yes
No significant ones
Local anesthesia
No
PRP
Cytokines & growth factors
All tissues (joints, tendons, ligaments, cartilage)
3-5 times at intervals
from 1-2 weeks
Yes (usually 1-2 years)
No
No
No significant ones
Local anesthesia
No
ACT
Cultured cartilage cells
Only cartilage tissue (joints)
Once
Yes (if not successful)
Yes
Yes
No significant ones
2 anesthetics required
Gradual increase in load. Fully resilient after one year.
Am I a suitable candidate?
Most patients are suitable for cell therapy. There are only a few exceptions.
For example, treated high blood pressure, taking blood-thinning medications, diabetes, obesity, old age or asthma are not a problem.
In the case of acute cancer, a risk assessment must be carried out in your personal case. There are no data or general recommendations for treating patients with acute cancer treatment or disease with cell therapy.
Age is no obstacle - the oldest patient, aged 94, shows no difference to the younger patients with a cell count of 50.4 million living cells.
Stem cell therapy is usually not indicated for children and adolescents, as the body's own regeneration potential is still high. The need for stem cell therapy under the age of 18 is certainly an exception and must be assessed on a case-by-case basis.